This week Jamie and I swapped the
grey streets of the City for the grey skies of Zurich , where we attended the Sachs
Associates 12th Annual Biotech in Europe Investor Forum. Overall the tone was
surprisingly upbeat – but perhaps inevitable, given the audience. It is some
time since I have heard the biotech sector described as ‘thriving’. But, the discussions
on investment, from the panellists in both VC and corporate venture funds,
raised some interesting points.
Overall there is a trend towards M&A
and collaborations in the sector; and while VC investments are on the decline,
corporate investment is supporting financings in the sector to a degree. Additionally,
the IPO market was described as ‘thawing’: over the past 12 months eight out of
the 26 IPOs in the sector globally were on European markets.
One of the most promising
projections was that by 2016, 70% of products on the market will have originated
from biotech companies, so biotechs are clearly developing good products and
Pharma can see the value.
While Pharma R&D budgets are
slashed, biotech is finding its influence growing and is actually starting to
drive the industry. But to drive the industry, there must be investment, and
investors are understandably cautious.
So what should a biotech do to
increase its chances of investment and, therefore, success?
To ensure commercial viability of a
product, first and foremost: “There must be significant patient benefit, even
if this increases the level of risk,” said Anja König of Novartis Venture
Funds, adding that “good management absolutely makes the difference between
success and failure.”
This sentiment was echoed by her
fellow panellists, along with the need for innovation and capital efficiency.
Carole Nuechterlein of Roche Venture Fund and Debbie Harland of SR One both
stressed the importance of the investor syndicate for several reasons. Investor
interests must be aligned so it is preferable to get in together early and be
able to take the Company through any further fundraisings to an exit. In
addition to the mechanics of the deal, the personalities are extremely
important and team work is essential.
“Companies and their investors will
go through tough times and biotech is a small industry built on relationships
and trust, in terms of both individuals and funds,” said Anja. This all plays
into ensuring that everyone has the same objective – some of the panellists said
at this point, that there were some funds with which they would not co-invest.
Finally, and perhaps most
importantly for successful drug discovery companies, “do the killer study!”
said Debbie. “Show if the product is a no-go, and stop it if it is not panning
out.”
Simone Elviss
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